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Research Associate I, Next Gen Sequencing

Job ID: req1823
Employee Type: exempt full-time
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public’s interest.  

 Position Overview:


The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research’s Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials.


  • Performs genomics research and/or assay development in collaboration with others for projects
  • Makes detailed observations, analyzes data and interprets results
  • Investigates, creates and develops new methods and technologies for project advancement
  • Maintains high level of professional expertise through familiarity with scientific literature
  • May participate in scientific conferences and contribute to scientific journals
  • May be responsible for identifying patentable inventions
  • May act as principal investigator in conducting own experiments
  • Exercises independent judgment in developing and/or modifying methods and techniques for solving scientific problems
  • Performs molecular assays by adherence to SOPs
  • Develops new assays and applies the methods/assays utilizing sound scientific judgement
  • Writes SOPs and performs formal reporting of research data, including presentations and/or scientific publications
  • Maintains knowledge of the most recent literature and scientific presentations relevant to projects
  • Maintains essential laboratory supplies and monitors equipment for optimum performance
  •  May be willing to assume supervisory roles as needed


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of a Bachelor’s degree in a related field from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) or four (4) years of experience in lieu of a degree.  Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the education requirement, a minimum of two (2) years of progressively responsible experience
  • Experience with next generation sequencing library creation and sequencing and/or molecular biology techniques
  • Ability to obtain and maintain a security clearance


Candidates with these desired skills will be given preferential consideration:

  • Experience in NGS genomic profiling assays
  • Experience in genomic assay development and workflow automation
  • Familiarity with clinical oncology studies and other protocol-driven clinical research
  • Experience working in clinical laboratory testing is highly desirable, but not required 


  • Proficient with Microsoft Office programs (Word, Excel, Powerpoint, Access)
  • Strong technical skills in molecular biological and genomic assays
  • Ability to independently evaluate the suitability and quality control of research or production assays or tests, develop and follow SOPs, and analyze and report data
  • Ability to track information in a large cohort of samples and monitor progress of multiple projects
  • Adequate computer skills to document, organize, and present experimental data
  • Strong critical thinking and problem solving skills
  • Ability to communicate effectively, both verbally and in writing


  • This position is subject to working with or have potential for exposure to animal(s) and/or animal material(s)
  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)