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Research Associate I, DNA QC (Cancer Genomics Research Laboratory)

Job ID: req1783
Employee Type: exempt full-time
Facility: Rockville: 9615 MedCtrDr
Location: 9615 Medical Center Drive, Rockville, MD 20850 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public’s interest.  

 Position Overview:


The Cancer Genomics Research Laboratory (CGR) investigates the contribution of germline and somatic genetic variation to cancer susceptibility and outcomes in support of the NCI's Division of Cancer Epidemiology and Genetics (DCEG), the world’s most comprehensive cancer epidemiology research group.  CGR is located at the NCI-Shady Grove campus in Gaithersburg, MD and operated by Leidos Biomedical Research, Inc.  We care deeply about discovering the genetic and environmental determinants of cancer, and new approaches to cancer prevention, through our contributions to the molecular, genetic, and epidemiologic research of the 70+ investigators in DCEG.  Working in concert with epidemiologists, biostatisticians and basic research scientists in DCEG’s intramural research program, CGR provides the capacity to conduct genome-wide discovery studies and targeted regional approaches to identify the heritable determinants of various forms of cancer. This includes the design and analysis of high throughput studies using various types of “–omics” technologies such as array- and sequence-based genome-wide association studies, studies of tumor characteristics using integrated genomic data analysis, and molecular epidemiologic studies based on novel assays focused on the metabolome and microbiome.


CGR is recruiting a Research Associate to work within our high throughput, highly automated sample staging laboratory to support biospecimen, reagent and materials management activities. The successful candidate will work seamlessly within the staging team tasked with delivering high quality biospecimens to support epidemiological cancer research at the DCEG.

  • Responsible for QC practices including nucleic acid quantitation and qualification, normalization, volume checking, and residual creation
  • Responsible for plating DNA on automation platforms
  • Use of LIMS for sample management
  • Responsible for performing, documenting, and reporting results for a variety of procedures in the laboratory, governed by SOPs
  • Ensure proper documentation of all laboratory processes performed in the laboratory


 To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical research or four (4) years relevant experience in lieu of degree.  Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the education requirement, a minimum of two (2) years of progressively responsible experience in a laboratory setting
  • Working knowledge of LIMS systems
  • Experience with robotics (use and maintenance, preferably with liquid handling systems)
  • Careful attention to detail and highly organized
  • Ability to troubleshoot and multitask
  • Ability to prioritize time and workload
  • Ability to work well in both a team environment as well as individually
  • Ability to effectively communicate to stakeholders
  • Computer literacy (Microsoft Office products, general computer proficiency)
  • Ability to obtain and maintain a security clearance


Candidates with these desired skills will be given preferential consideration:

  • Understanding of nucleic acid extraction processes
  • Experience working with nucleic acid quantitation instrumentation including TapeStation and Nanodrop
  • Experience with Tableau software


  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations
  • This position is subject to the environmental conditions such as working outdoors, high humidity areas indoors, dampness and chilling, dry atmospheric conditions, etc. as part of the job

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)