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RAS Initiative Postdoctoral Fellow

Job ID: req1760
Employee Type: exempt full-time
Facility: ATRF: Other
Location: 8560 Progress Drive, Frederick, MD 21701 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public’s interest.  

 Position Overview:

PROGRAM DESCRIPTION

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.

KEY ROLES/RESPONSIBILITIES

The RAS Post Doctoral Fellow will:

  • Perform biophysical measurements to analyze small G-protein- lipid interactions
  • Quantitate the activity of RAS in biological membranes
  • Conduct independent research
  • Analyze data and present research findings to other scientists
  • Stay informed of the latest findings in RAS and membrane biology
  • Submit manuscripts for peer reviewed publication
  • Collaborate with other members of the program or with external institutions

BASIC QUALIFICATIONS

  • Possession of a PhD degree from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) in science or eight (8) years of related experience.  Foreign degrees must be evaluated for U.S. equivalency
  • Expertise with biophysical experiments using artificial lipid bilayers
  • Knowledge of biophysical tools to measure protein - protein and protein - membrane interactions
  • Experience with fluorescence spectroscopy
  • Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS 

Candidates with these desired skills will be given preferential consideration:

  • Demonstrated publication record
  • Experience working on RAS or other small GTPases

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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