SARS-CoV-2 Serology Research and Development Associate
Job ID: req1592
Employee Type: exempt full-time
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA
The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.
Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public’s interest.
The Clinical Services Program's primary mission is to perform sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease or other diseases associated with immunologic dysfunction, as well as to monitor viral load in patients with HIV.
The Vaccine, Immunity and Cancer Program investigates immune responses to vaccines in preclinical and clinical studies, with a focus on HPV and more recently on SARS-CoV-2.
The Vaccine, Immunity and Cancer Program is looking for Research Associate II to conduct serology research and testing for SARS-CoV-2. The aims of this project are to produce critical assay reagents and perform serology and other immune assays for assessment of immune responses to infection and vaccines.
The Research Associate II will:
- Be responsible for sample management
- Optimize and validate procedures and methodologies for assessment of immune responses to infections and vaccines
- Plan experiments and conduct testing of large number of samples from clinical studies
- With limited supervision, design and implement protocols, as well as troubleshoot assays and experiments independently
- Evaluate, analyze and compile data, maintain databases
- Responsible for routine QC/QA procedures, ordering supplies, and maintaining equipment and inventories
- Prepare reports, present data and participate in report and proposal preparation
- Remain current on literature and relevant laboratory techniques
- Ability to obtain and maintain a security clearance
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
- Possession of Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency.
- In addition to the education requirement, a minimum of five (5) years of laboratory experience
Candidates with these desired skills will be given preferential consideration:
- Experience in standard tissue culture and immunological/virological techniques, including: aseptic techniques, cell line maintenance, production of plasmids and virus-like particles, western-blot, ELISA, Luminex assays, virus neutralization assays and PCR
- Experience in immune assay (ELISA, multiplex assays) development and validation
- Experience handling large data sets, statistics, software tools (Word, Excel, PowerPoint)
- Experience in laboratories operating under GCLP/GMP/GLP/CLIA
- Experience using robotics
- Experience with electronic documentation systems and LIMS
- This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations
Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)