Post Doctoral Fellow - Molecular Virology/HIV Virology
Job ID: req1471Employee Type: exempt full-timeFacility: Frederick: Ft DetrickLocation: PO Box B, Frederick, MD 21702 USA
The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases. Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public’s interest.
Position Overview:
PROGRAM DESCRIPTION
The Laboratory of Human Retrovirology and Immunoinformatics (LHRI), Applied/ Developmental Directorate, has investigated mechanism of multiple-class drug resistant (MDR) in HIV infection. We have produced recombinant MDR from patients infected with MDR and characterized pathogenesis and innate immune response in of MDR infection. Goals of the studies are to define salvage therapies for each patient and to develop novel anti-viral therapy using either chemical compounds (nucleotide, peptide or others) or immune regulatory proteins (cytokines or other proteins). In the course of study, LHRI has discovered novel MDR mutations, and reported Interleukin-27 and some novel none-coding RNAs as novel anti-viral materials. In this position, candidates will investigate mechanism(s) of potential anti-viral drugs/chemical compounds in anti-HIV and off-target effect on host cell responses to elucidate a potent side effect.
KEY ROLES/RESPONSIBILITIES
The Postdoctoral Fellow will be involved in:
BASIC QUALIFICATIONS
PREFERRED QUALIFICATIONS
JOB HAZARDS
Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)#readytowork
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